New technology can create treatment against drug-resistant bacteria in under a week and adapt to antibiotic resistance


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The big idea

A new technique my colleagues and I developed that can kill deadly, multidrug-resistant bacteria in real time could be used to generate targeted therapies that replace traditional, increasingly ineffective antibiotics.

Bacteria follow the same basic genetic process that all organisms do: DNA, which contains instructions on how an organism will look and function, is copied into an intermediate form called RNA that can be translated into proteins and other molecules the organism can use.

The technique we developed at the Chatterjee Lab at the University of Colorado Boulder uses a synthetic version of RNA called PNA, or peptide…

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